王桂荣课题组

　　王桂荣课题组

　　Wang Guirong Lab

　　课题组长

　　王桂荣, 研究员, 博士生导师。王桂荣研究员一直围绕“害虫化学生态学”开展应用基础研究，比较系统地研究了害虫嗅觉编码的神经和分子机制，在此基础上提出以气味受体为靶标，通过体外重建气味受体的功能高通量筛选害虫行为调控的新策略，为发展绿色环保的害虫防治策略提供了新思路和新方法。获得国家自然科学基金杰出青年科学基金，入选国家重大人才工程领军人才、人社部国家“百千万”人才工程、科技部创新人才推进计划，国务院特殊津贴专家，国家有突出贡献中青年专家。在PNAS、Current Biology、Biological Reviews等杂志上发表研究论文100余篇。

　　工作经历

　　2019.5-至今中国农业科学院（深圳）农业基因组研究所研究员，博士生导师

　　2011.1-至今中国农业科学院植物保护研究所研究员，博士生导师

　　2005.1-2010.12 中国农业科学院植物保护研究所副研究员，硕士生导师

　　2005.3-2010.10 美国Vanderbilt大学 Senior/Research Associate

　　2002.9-2005.1 中国农业科学院植物保护研究所助理研究员

　　2002.7-2002.9 中国农业科学院植物保护研究所实习期

　　学习经历

　　1999.9-2002.7 中国农业科学院研究生院获博士学位

　　1996.9-1999.7 中国农业科学院研究生院获硕士学位

　　1992.9-1996.7 安徽师范大学生物系大学本科

　　研究方向

　　基于农业害虫绿色防控的国家重大需求，遵循“源于自然、用于自然、回归自然”的理念，通过重大农业害虫全基因组测序和生物信息学分析结合功能组学研究，挖掘高效、安全的农业害虫特异性的分子靶标，通过结构解析、分子对接和基于功能研究的高通量筛选，研发用于害虫生长发育调控、行为调控和生态调控的、环境友好的新型绿色农药。

　　Professor Guirong Wang has long been engaged in the study of pest insect olfactory coding mechanisms, and has some contribution in the field including the neural and molecular mechanisms through which external chemical signals are transformed into electrical signals in the insect. These achievements have contributed novel knowledge and technology to facilitate the development of sustainable pest management strategies. He has published more than 100 research papers including in Current Biology, PNAS and Biological Reviews. He has been granted 6 Chinese invention patents, and serves as an editorial board members for several international journals.

　　Research Interests

　　Based on the country's major needs for green pest control, follow the concept of “derived from nature, used for nature, return to nature”, through the whole genome sequencing of major agricultural pests and bioinformatics analysis combined with functional omics research, to find efficient and safe Agricultural pest-specific molecular targets, through structural analysis, molecular docking and high-throughput screening based on functional research, develop new environmentally friendly green pesticides for pest growth and development regulation, behavior regulation and ecological regulation　　

　　Selected Publication　　

　　1、Hetan Chang, Yang Liu, Dong Ai, Xingchuan Jiang, Shuanglin Dong, Guirong Wang* A pheromone antagonist regulates optimal mating time in the moth, Helicoverpa armigera. Current Biology, 2017, 27(11): 1610-1615

　　2、R Zhang, B Wang, G Grossi, P Falabella, Y Liu, S Yan, J Lu, J Xi, G Wang* Molecular Basis of Alarm Pheromone Detection in Aphids, Current Biology (2017), 27(1):55-61

　　3、Zhu J, S Arena, S Spinelli, D Liu, G Zhang, R Wei, C Cambillau, A Scaloni, G Wang*, P Pelosi*. Reverse Chemical ecology: Olfactory proteins from the giant panda and their interactions with putative pheromones and bamboo volatiles. PNAS, 2017, 114(46): E9802-E9810.

　　4、Paolo Pelosi, ImmacolataIovinella, Jiao Zhu, Guirong Wang*, Francesca RomanaDani*. Beyond chemoreception: different tasks of soluble olfactory proteins in insects. Biological Reviews. 2018, 93: 184-200.

　　5、Feng-qi Li, Wei Li, Yong-Jun Lin, John A. Pickett, Michael A. Birkett, Kongming Wu, Guirong Wang*, Jing-Jiang Zhou*. Expression of Lima Bean Terpene Synthases in Rice Enhances Recruitment of a Beneficial Enemy of a Major Rice Pest. Plant, Cell & Environment. 2018,41:111-120.

　　6、Bing Wang, Yang Liu * and Gui-Rong Wang*. Chemosensory genes in the antennaltranscriptome of two syrphid species,Episyrphusbalteatus and Eupeodes corolla(Diptera: Syrphidae). BMC Genomics (2017) 18:586

　　7、J Wei, T Fu, D Cao, T Yang, Y Liu, G Wang*. A TRPA1 channel that senses thermal stimulus and irritating chemicals in Helicoverpaarmigera. Insect Molecular Biology. 2015, 24(4): 412-421.

　　8、Liu C, Liu Y, Walker WB, Dong SL*, Wang GR*. Identification and functional characterization of sex pheromone receptors in beet armyworm Spodopteraexigua (Hübner). Insect Biochemistry and Molecular Biology 43 (2013) 747-754

　　9、J Zhu, I Iovinella, F Romana Dani, Y Liu, L Huang, Y Liu, C Wang, P Pelosi*, G Wang*. Conserved chemosensory proteins in the proboscis and eyes of Lepidoptera.IJBS, 2016 12(11): 1394-1404

　　10、Fu T, Hull JJ, Yang T, Wang G* Identification and functional characterization of four transient receptor potential ankyrin 1 variants in Apolyguslucorum (Meyer-Dür).Insect Mol Biol. 2016, 25(4):370-384.

　　11、H Chang, M Guo, B Wang, Y Liu*, S Dong, G Wang*. Sensillar expression and responses of olfactory receptors reveal different peripheral coding in two Helicoverpaspecies using the same pheromone components. Scientific Reports. 2016, 6:18742. 1

　　12、Jin Zhang, Shuwei Yan, Yang Liu, Emmanuelle Jacquin-Joly, Shuanglin Dong, Guirong Wang*. Identification and Functional Characterization of Sex Pheromone Receptors in the Common Cutworm (Spodopteralitura). Chemical Senses. 2015, 40(1):7-16.

　　13、D Cao, Y Liu, J Wei, X Liao, W B. Walker, J Li, G Wang*. Identification of candidate olfactory genes in Chilo suppressalis by antennal transcriptome analysis. International Journal of Biological Sciences. 2014, 10(8): 846-860

　　14、Wang GR, Allison Carey, John R. Carlson and Laurence J. Zwiebel*. The Molecular Basis of Odor Coding in Malaria Vector Mosquito Anopheles gambiae. PNAS2010, 107(9):4418-23

　　15、Allison Carey, Guirong Wang, Chih-Ying Su, Laurence J. Zwiebel, and John R. Carlson*. Odorant reception in the malaria mosquito Anopheles gambiae. Nature 2010 464(7285):66-71.

　　16、Wang GR, Y.T.Qiu, T. Lu, H.Kwon, R. J.Pitts, J.J. van Loon, W.Takkenand L.J. Zwiebel*. Anopheles gambiae TRPA1 is a heat-activated channel expressed in thermosensitivesensilla of female antennae. European Journal of Neuroscience. 2009, 30: 967-974.

　　17、Y.F. Xia, Wang GR(first co-author), D Buscariollo, R.J. Pitts, H. Wegnerand L.J. Zwiebel*. The Molecular and Cellular Basis of Olfactory Behavior in Anopheles gambiae Larvae. PNAS. 2008, 105(17):6433-8.

　　18、T. Lu,YT. Qiu, Wang GR (first co-author), J.Y. Young, M.Rutzler, H.W. Kwon, R. J. Pitts, J. J.A. van Loon, J. R. Carlson, W.Takken, and L. J. Zwiebel*. Odor Coding in the Maxillary Palp of the Malaria Vector Mosquito Anopheles gambiae. Current Biology. 2007, 17(18): 1533-1544

王桂荣课题组更新于2020年7月

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